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KMID : 0390119930330020241
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Journal of Pusan Medical College
1993 Volume.33 No. 2 p.241 ~ p.246
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A Clinical Study of the mediastinal Tumors in Children
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Abstract
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Mediastnum can be devided into three or four sections. Each section has different organ contents and so has it's specific pathological types of mediastinal tomors. In children, the rate of malignant versus benign neoplasm of mediastinum is higher
than
adult. Acording to pathological types of neoplasm, they differ in clinical manifestations, management policy, and long term results. The author analized medical records of 30 patients less than 16 years of age who were evaluated and treated for a
mediastinal mass at the Department of Pediatrics and Thoracic Surgery, Pusan National University Hospital from Jan. 1980 to December 1990.
Of the 30 patients, 17 were male and 13 were female. School age children and adolescents were the majority(63%) of the patients. The most common cause of mediastinal masses were neurogenic tumors(26.7%). Malignant lymphomas were seen in 23.3% of
patients and leukimias in 13.3%. Thirteen patients had benign lesions and 17 had malignant lesions. Of 13 patients with benign tumors, 3 patients had neurofibromas, 5 patients had thymic origin tomors 2 patient had bronchogenic cysts, and anoter
2
patients teratomas. Of 17 patients with malignant tomors, 7 patients had lymphomas, 4 patients leukemias, 3 patients neuroblastomas, and 2 patients ganglioblastomas. Temn patients(33%) and superior mediastinal tumors of which 4 cases were
non-Hodgekin's
lymphom a and 3 case were mediastinal infiltrations of acute lymphocytic lymphocytic leukemias. Nine patients had posterior mediastinal tumors of which 8 cases were neurogenic tumors. In 5 cases, masses were found at superior mediastinum, of
which
2
cases were thymomas. There were 3 middle mediastinal tumors of which 2 cases were non-Hodgekin's lymphomas.
As cardinal symptoms, respiratory symptoms such as cough, chest pain and dyspnea were complained of most(70%). Neurologic symptoms such as walking disturbance, paraplegia, ptosis were complained of in 5 patients. There were 7 asymptomatic cases
also.
All patients with benign tumors had surgical excisions, and patients with malignant tumors had surgical excisions and chemotherapy(in 2 patients), or excisions with irradiations(in 2 patients), chemotherapys and irradiations(in 6 patients) and
chemotherapys only(in 6 patients).
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